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The best weapons to use for the boss battle are the Contact beam and the pulse rifle. The reason for this is because the alt fire of the Contact beam is perfect for keeping the pack away while you fire at Nicole and the Heart ( assuming the have the special ability of the Contact beam upgraded, causing the alt fire to stasis all enemies surrounding you). The Detonator could also be useful, as strategic placement of the mines can keep the pack away. Using this method, I have successfully beat the boss level (IN ZEALOT MODE) in under 5 minutes, and hopefully, you can too!
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