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Dr. Isabel Cho was one of the four survivors from the USG O'Bannon incident. 


Aegis VII[]

Isabel Cho was the Chief Medical Officer on board the USG O'Bannon. She was one of the few crew members besides Nolan Stross, Rin, Nickolas Kuttner and Captain Caleb Campbell to know about the true intentions of the mission which involved gathering any remaining Marker 3A fragments from the colony on Aegis VII.

The crew landed on an unstable Aegis VII and headed out to look for the surviving fragments of the Red Marker. Kuttner found one of them and started to hallucinate Cho and her teammates as monsters, eventually killing Alejandro Borges' cousin, Noah Pawling. Cho tried to save Noah, but it was too late. The structurally unstable Aegis VII began to explode and only her, Stross, Borges and Kuttner survived, crashing back into the O'Bannon and eventually giving the Marker fragment to Captain Campbell.

Cho took care of a very confused and disorientated Kuttner while overseeing the bodies of all of those that were killed when the O'Bannon was damaged by Aegis VII's explosion. During this, Cho was involved in an affair with Nolan Stross which had begun several months before the mission. Stross had told Cho that he was going to leave his family, and Cho tried to distance herself from him for this reason, ultimately failing due to the fact that she loved Stross too much and was too happy with him to give up even knowing that he had a wife and child.

Cho and her medical team went to check on the bodies in the morgue only to discover that they were gone, before the mutilated corpse of one of the doctors soon transformed into a Necromorph and killed all except Cho. Cho made it to the room where Kuttner was being held and released him before he killed the Necromorph. Isabel and Kuttner made it to Stross' suite to discover that he had killed his wife Alexis and his baby son in his hallucinations. Cho was horrified by this and began to bitterly refuse to have conversations with Stross.

Isabel, Stross and Kuttner met up with Captain Campbell, Alejandro and two other crew members, Lt. Marcus and Lana. They discussed how to stop the outbreak and Stross revealed that the Marker shard could only be destroyed by being thrown into the reactor core. The team set off toward the engine room, but Lana noticed her roommate, Jenny, seemingly crying in a corner and ignored Cho's warning about getting too close to her. As Lana got close enough, she discovered that Jenny had turned into a Grabber which then spat acid into Lana's face. The skin on Lana's face was dissolved, but despite her horrific injuries, she survived the attack. She later died due to a grenade blast. Lt. Marcus was soon killed as well when a Necromorph attacked him which led to him being sucked out of the hull's breach and into space.

Kuttner was almost sucked out of the ship as well, but was reluctantly saved by Borges. After the remaining survivors made it into the airlock, Stross gave them the unfortunate news that the airlock's seal was broken on their side and could only be sealed from the outside. Feeling guilty and responsible for all of the deaths of his crew on Aegis VII and on his ship, Captain Campbell volunteered to be the one to seal the airlock. After arguing with his remaining shipmates, Captain Campbell ordered them to destroy the shard, and as he exited the airlock, he told them to tell his wife that she was right and he should have retired before journeying to Aegis VII. After sealing the doors, he pulled out an incendiary grenade, jumped into the crowd of Necromorphs and caused a second hull breach outside of the sealed door, causing all of the remaining Necromorphs to fly into space.

Cho collapsed after watching Campbell's sacrifice. The group then made it to the engine room only to be attacked by several Necromorphs. Cho managed to keep them at bay, but Stross once again became hypnotized by the fragment, to which Cho responded by running up to him and striking him. Cho then grabbed the fragment and before it could have any effect on her, she tossed it into the core, destroying it and all of the Necromorphs which turned into small puddles of what was described as "organic soup" by other witnesses.

Discovery and Interrogation[]


Isabel aboard the USM Abraxis.

A squad of five Marines entered the O'Bannon to discover that all of its crew members were dead except four. The Marines took Cho, Stross, Borges and Kuttner and brought them aboard the USM Abraxis. After Borges and Kuttner did not return from their interrogations, Cho began to worry just before Stross replied by telling her that they were dead as he could "feel" it. Stross was next to be interrogated before Cho. After Isabel was interrogated, she was confronted by a member of EarthGov, the Overseer, who offered her a job on the Marker research project. Cho was horrified by this and declined, telling him that she would not stand for this as she realized that EarthGov had the whole event on the O'Bannon planned all along. The Overseer told her that he was sorry that she felt that way before she was grabbed and lobotomized in order to keep her quiet.

At the Sprawl[]

Terrorist isabel cho dead space aftermath

Isabel Cho after her framing and lobotomization.

Cho was used as a scapegoat by EarthGov in order to cover up the Necromorph outbreak on Aegis VII, the USG Ishimura and the O'Bannon. The public was told that Cho was a terrorist linked to the massacres in the Aegis system, and that she was held at the Sprawl to be tried for her "crimes".


  • Isabel Cho was voiced by Gwendoline Yeo and her CGI-animated character was also based on her likeness.
  • The Lead Interrogator told Cho that she had a fine mind and a strong will, indicating that, had she come into direct contact with the Marker shard, its signal could have "resonated" with her.
  • It was suggested that Cho had a Korean background as she stated that she could only speak English and Korean.
  • Unlike the other three survivors of the O'Bannon, Isabel's exact phobia was never revealed, as it was just skipped over to a scene where she was gasping for air. This may be hinting toward hydrophobia or a rape scenario.
  • In the falsified news report branding her a terrorist, an image of her was shown with a blank expression and a red spot on her forehead, which was evidence of her lobotomy.
  • In Dead Space 2, Cho was only mentioned in the name of an audio log, "Framing Cho".